USA captain Nick Varner has warned his European opponents: We're here to win the cup back.
A presentation evening took place at the Shibuya restaurant at the MGM Grand Hotel and Casino ahead of the start of the event on Thursday.
Both captains made speeches, while all players from both sides were announced to a small set of fans, officials and sponsors.
Varner said: "The Mosconi Cup has always been the most exciting event in pool. Team play brings a lot more excitement to the game and with the Mosconi Cup I found that out first hand.
"This year we've got three new players with Oscar Dominguez and Dennis Hatch making their first appearances while we didn't have Corey Deuel last year.
"Then we have Shane Van Boening making his third appearance and then hall of famer Johnny Archer. Barry Hearn has previously said that Johnny is the back bone of the US team.
"I'm really happy with my team and we have a strong team. I would like to thank the promoters, Barry Hearn and his staff, all the sponsors and Sky Sports - we're going to have a ball this week.
"My team has a message for Team Europe. You have the cup, but we want the cup and Team USA is coming to get that cup."
European captain Alex Lely, who guided his side to victory last year, added: "This is the 16th event and I've played in two Mosconi Cups but by best moment was last year even though I never held a cue. It was great to win in Malta but now in Las Vegas we're in the lions' den.
"Europe is gaining momentum and we've not reached maximum speed yet. We have five World Champions and I'm really looking forward to this week.
"We're here to retain the cup and we have the heart, pride and passion to do so. Enjoy the show."